Background

References

References

  • 1.Based on internal analysis by iNova Pharmaceuticals (Pty) Ltd using data from the following source: IQVIA Rx_OTC Jul 2023, ATC3- A8A, Brands measured in Dispensed Units, reflecting estimates of real-world activity. Copyright IQVIA. All rights reserved
  • 2.Data on File
  • 3.Product approved package insert, July 2000.
  • 4.Dietary Supplements for Weight Loss - Health Professional Fact Sheet, July 2021.
  • 5.Mendieta-Zerón H, López M, Diéguez C. Gastrointestinal peptides controlling body weight homeostasis. Gen Comp Endocrinol 2008;155(3):481-495.
  • 6.Yu JH, Kim M-S. Molecular Mechanisms of Appetite Regulation. Diabetes Metab J 2012;36(6):391-398.
  • 7.Crujeiras AB, Carreira MC, Cabia B, et al. Leptin resistance in obesity: An epigenetic landscape. Life Sci 2015;140:57-63.
  • 8.Sumithran P, Prendergast LA, Delbridge E, et al. Long-Term Persistence of Hormonal Adaptations to Weight Loss. N Engl J Med 2011;365(17):1597-604.
  • 9.Berthoud H-R. Interactions between the "cognitive" and "metabolic" brain in the control of food intake. Physiol Behav 2007;91:486-498.
  • 10.Rosenbaum M, Kissileff HR, Mayer LES, et al. Energy Intake in Weight-Reduced Humans. Brain Res 2010;1350:95-102.
  • 11. National Health and Medical Research Council. Clinical practice guidelines for the management of overweight and obesity in adults,adolescents and children in Australia, 2013.
  • 12.Q&A with Dr Riekie Smit - 26 January 2021
  • 13.https://thechalkboardmag.com/summer-body-diet-fitness-tips
  • 14.Transcript of telephonic interview with Claire Strydom, 15 April 2020.
  • 15.University of Rochester Medical Center. Winter Weight Gain: Why it Happens, What to do (2020) at https://www.urmc.rochester.edu/patients-families/health-matters/january-2020/winter-weight-gain-why-it-happens-what-to-do.aspx(website accessed 17 February 2020).
  • 16.Q&A with Dr Colinda Linde –11 February 2020 (unpaid)
  • 17.Q&A with Dr Riekie Smit –13 February 2020 (unpaid)
  • 18.Mayo Clinic - Mediterranean diet: A heart-healthy eating plan (2019) at https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/mediterranean-diet/art- 20047801
  • 19.Moldovan CP, Weldon AJ, Daher NS, Schneider LE, Bellinger DL, Berk LS, et al. Effects of a Meal Replacement System Alone or in Combination with Phentermine on Weight Loss and Food Cravings. Obesity 2016; 24:2344-2350.
  • 20.NHLBI Obesity Education Initiative Expert Panel on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults. The practical guide identification, evaluation, and treatment of overweight and obesity in adults. NIH Publication Number 00-4084; October 2000.
  • 21.Government Gazette. Republic of South Africa. Regulation Gazette number 10203.29 May 2014;587(37695):1-112. [online] 2014 [cited 2019 December 9]; Available from URL: http://www.gpwonline.co.za/Search/Pages/gazetteresults.aspx?k=37695.
  • 22. Conlon KE, Ehrlinger J, Eibach RP, et al. Eyes on the prize: The longitudinal benefits of goal focus on progress toward a weight loss goal. J Exp Soc Psychol. 2011;47(4):853–855. doi:10.1016/j.jesp.2011.02.005
  • 23.Phelan S, Wadden TA. Combining Behavioural and Pharmacological Treatments for Obesity. Obes Res 2002;10(6):560-574
  • 24.Mayo Clinic Hypothyroidism (underactive thyroid) (2020) at https://www.mayoclinic.org/diseases-conditions/hypothyroidism/symptoms-causes/syc-20350284 (Website accessed on 2 May 2022)
  • 25. MedicineNet. Can Hormonal Imbalance Cause Weight Gain? (2020) at https://www.medicinenet.com/can_hormonal_imbalance_cause_weight_gain/article.htm (Website accessed on 2 May 2022)
  • 26. Medical News Today. What to know about insulin and weight gain (2019) at https://www.medicalnewstoday.com/articles/325328#tips-to-avoid-weight-gain (Website accessed on 3 May 2022)
  • 27. Raleigh L. 46 Benefits of rebounding. Available online: https://www.lisaraleigh.com/pages/46-benefits-ofrebounding? gclid=CjwKCAjw9NeXBhAMEiwAbaY4ln59iFjVAljPqEV5gk7xaSHpkQg0iFvDu7f4oFkshEAtXlWWHEoYOhoCgfMQAvD_BwE
  • 28. World Health Organization. (2020) Available online: https://www.who.int/news-room/fact-sheets/detail/physical-activity.
  • 29.CDC. Healthy Eating for a Healthy Weight (2021) at https://www.cdc.gov/healthyweight/assessing/index.html. (Website accessed on 10 October 2022)
  • 30.Urban Fitness Solutions. 12 Key Fundamentals of losing weight (2021) at https://www.urbanfitness.com.au/blog/weight-loss/12-key-fundamentals-of-losing-weight. (Website accessed on 10 October 2022)
  • 31.Medical Associates of North Texas. Why Hormone Imbalance Can Make It Hard to Lose Weight (2022) at https://www.mantcare.com/blog/why-hormone-imbalance-can-make-it-hard-to-lose-weight. . (Website accessed on 10 October 2022).
  • 32.Sorgen C. Why aren't you losing weight? (2004) at https://www.webmd.com/diet/obesity/features/why-arent-you-losing-weight. (Website accessed on 10 October 2022).
  • 33.Karen Eisenbraun. Keys to weight loss are commitment and patience (2017) at https://garciaweightloss.com/blog/keys-weight-loss-commitment-patience/. (Website accessed on 10 October 2022).
  • 34.Q&A with Dr RiekieSmit – June 2021 (unpaid)
  • 35.Phelan S, Wadden TA. Combining Behavioural and Pharmacological Treatments for Obesity. Obes Res 2002;10(6):560-574.
  • 36.Hainer V. Management of obesity in adults: Project for European primary care. Int J Obesity 2004;28:S226–S231.
  • 37.Katz DA, McHorney CA, Atkinson DL. Impact of Obesity on Health-related Quality of Life in Patients with Chronic Illness. J Gen Intern Med 2000;15:789-796
  • 38. Munro JF, Maccuish A. C, Wilson EM, Duncan LJP. Comparison of Continuous and Intermittent Anorectic Therapy in Obesity.
  • 39.Lifshitz F. Obesity in Children. J Clin Res Ped Endo 2008;1(2):53–60
  • 40.40. The American Heart Association. Healthy for Good [online] 2020 [cited 20 September 2023]; Available from: https://www.heart.org/-/media/AHA/H4GM/PDF-Files/Eat_More_Color_infographic.pdf
  • 41.Rabeie S, Nazari M. Effects of Food Plate Size and Color on Visual Perception of Satiety in Adolescents; a New Strategy toward Weight Management. Iran J Public Health 2023;52(6):1289-1296
  • 42.Westcott WL. Resistance Training is Medicine: Effects of Strength Training on Health. Current Sports Medicine Reports 2012;11(4):209-216.
  • 43.Ross A, Brooks A, Touchton-Leonard K, et al. A Different Weight Loss Experience: A Qualitative Study Exploring the Behavioral, Physical, and Psychosocial Changes Associated with Yoga That Promote Weight Loss. Evidence-Based Complementary and Alternative Medicine 2016: Article ID 2914745. http://dx.doi.org/10.1155/2016/2914745.
  • 44.McDonnell K. Popcorn Nutrition Facts: A Healthy, Low-Calorie Snack? [online] 2017 [cited 3 October 2023]; Available from: https://www.healthline.com/nutrition/popcorn-nutrition-and-health#:~:text=Eating%20It%20May%20Help%20With,than%20many%20popular%20snack%20foods.
  • 45.Frey M. Best and Worst Snack ChipChoices in NutritionCompare Calories in Potato Chips and Other Snacks [online April 2023] [cited 3 Octover 2023]; Available from: https://www.verywellfit.com/the-best-and-worst-chip-choices-calories-in-top-picks-4117844#:~:text=The%20Least%20Nutritious%20Snack%20Chip,and%202%20grams%20of%20protein.
  • 46.Cronometer [Online] [cited: 4 October 2023]. Available at: https://cronometer.com/#search-foods
  • 47.Harvard T.H. Chan School of Public Health. The Nutrition Source. Healthy Eating Plate [online] 2023 [cited 3 October 2023]; Available from: https://www.hsph.harvard.edu/nutritionsource/healthy-eating-plate-vs-usda-myplate/
  • 48.Nelson JB. Mindful Eating: The Art of Presence While You Eat. Diabetes Spectr 2017;30(3):171–174.
  • 49.CDC ref: Centers for Disease Control and Prevention. Heath Effects of Overweight and Obesity [online ]September 2022 [cited 7 February 2024]; Available from: https://www.cdc.gov/healthyweight/effects/index.html.
  • 50.Healthline ref: Want to Lose Weight Fast? TheseScience-Backed Tips Can Help You LoseWeight Sustainably [online] October 2023 [cited 7 February 2024]; Available from: https://www.healthline.com/nutrition/how-to-lose-weight-as-fast-as-possible
  • 51.The training Room. Mastering Portion Control for Your Fitness Goals: A Comprehensive Guide. [Online] 2024 [Cited on 30 April 2024] Available from: https://trainingroomohio.com/
  • 52.Healthline. 12 Simple Ways to Drink More Water. [Online] 2023 [Cited on 30 April 2024] Available from: https://www.healthline.com/nutrition/how-to-drink-more-water#TOC_TITLE_HDR_14
  • 53.NutriFundi. Importance of Hydration. [Online] 2024 [Cited on 30 April 2024] Available from: https://www.nutrifundi.co.za
  • 54.Ritz P, Berrut G. The importance of good hydration for day-to-day health. Nutr Rev. 2005;63(6 Pt 2):S6-S13. doi:10.1111/j.1753-4887.2005.tb00155.x
  • 55. Raman R. How to Get Rid of Visceral Fat [online] April 2023 [cited 11 April 2024]; available from: https://www.healthline.com/nutrition/lose-visceral-fat#TOC_TITLE_HDR_11.
  • 56. Cleveland Clinic. Visceral Fat [online] [cited 11 April 2024}; Available from: https://my.clevelandclinic.org/health/diseases/24147-visceral-fat.
  • 57. British Heart Foundation. How to avoid winter weight gain [online] December 2022 [cited 11 April 2024]; Available from: tps://www.bhf.org.uk/informationsupport/heart-matters-magazine/nutrition/weight/avoiding-winter-weight-gain